Explainers

Plain-English explanations of MEF2C research terms, concepts, and scientific mechanisms.

Blood-Brain Barrier (BBB) Penetrance

The Blood-Brain Barrier (BBB) is like a **military checkpoint** between your bloodstream and your brain. It's made of tightly packed cells with no gaps — designed to keep toxins out. But it also keeps...

Blood-Brain Barrier (BBB)

**What it means:** The BBB is an ultra-tight layer of cells lining the brain's blood vessels. Think of it like a **super-filter** or a nightclub with an extremely strict bouncer — it lets nutrients an...

Serotype (AAV Serotype)

**What it means:** AAV isn't a single virus — it's a family of related viruses, each called a **serotype**. Different serotypes have different **tissue preferences** — some are better at reaching the ...